Benefits of ACCRUFeR

You deserve a tolerable iron treatment that you can actually stick with

ACCRUFeR^® (ferric maltol) is an effective, low-dose treatment for patients with iron deficiency (ID) or iron deficiency anemia (IDA).

Woman standing, stomach and ACCRUFeR "maltol shield" graphic overlay

Why ACCRUFeR?

ACCRUFeR was studied in patients with inflammatory bowel disease (Crohn’s disease or ulcerative colitis) and chronic kidney disease (stages 3 or 4). However, it is FDA approved for other adults with ID and IDA as well.

Here are a few reasons why ACCRUFeR may be right for you!

The iron in ACCRUFeR is shielded by a substance called maltol. The “maltol shield” keeps iron protected from the stomach, so it doesn’t break down until it is ready to be absorbed in the small intestine. By limiting the amount of unabsorbed iron in the body, there is a lower risk for intolerable gastrointestinal side effects.

Across studies, fewer than 5% of patients taking ACCRUFeR discontinued treatment because of side effects.*

*Total of 175 patients across studies

ACCRUFeR was proven effective in multiple studies over short-term (12 to 16 weeks) and long-term (52 to 64 weeks) periods. Patients on ACCRUFeR experienced significant improvements in their iron levels compared with those on a placebo.

Patients take a low 30 mg dose of ACCRUFeR twice per day. With this dosing, patients in clinical studies did not require IV iron intervention, and treatment did not lead to iron overload.

Iron you’ll actually take

Traditional oral iron supplements were not effective in patients enrolled in two of ACCRUFeR’s clinical trials. About 40% reported intolerable gastrointestinal side effects as the reason they stopped taking their supplement.

In ACCRUFeR's clinical studies, side effects were considered mild to moderate in nature. Some of the most common side effects included:

Gas
Diarrhea
Constipation
Discolored feces
Abdominal pain

Give your stomach a break

Fewer than 5% of the individual patients taking ACCRUFeR (out of 175) reported each of the individual GI-related side effects.

Our Clinical Studies

Review the results for patients in clinical studies.

How ACCRUFeR Works

Learn about ACCRUFeR’s “maltol shield” and how it helps minimize gastrointestinal side effects.

IMPORTANT SAFETY INFORMATION

Do not take ACCRUFeR if you are allergic to ferric maltol or any of the ingredients in ACCRUFeR; have any illness that causes you to store too much iron in your body or if you have a problem with how your body uses iron; are receiving repeated blood transfusions.

Before you take ACCRUFeR, tell your doctor about all your medical conditions, including if you have inflammatory bowel disease (IBD); are pregnant or plan to become pregnant (it is not known if ACCRUFeR will harm your unborn baby; talk to your doctor if you are pregnant or plan to become pregnant); are breastfeeding or plan to breastfeed (it is not known if ACCRUFeR passes into your breast milk); talk to your doctor about the best way to feed your baby if you take ACCRUFeR.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Taking ACCRUFeR and certain other medicines may interact, which could potentially cause serious side effects. Some medicines may need to be taken at least 4 hours before or 4 hours after you have taken ACCRUFeR. Ask your healthcare provider for a list of these medicines if you are not sure if you take one of these medicines.

Especially tell your healthcare provider if you take:

Dimercaprol

Other oral iron tablets or health supplements containing iron

Ask your healthcare provider if you are not sure if you take one of these medicines. Know the medicines you take. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.

What are the possible side effects of ACCRUFeR?

ACCRUFeR may cause serious side effects including:

Increased risk of inflammatory bowel disease (IBD) flare. You should avoid taking ACCRUFeR if you have IBD and are experiencing a flare

Too much iron stored in your body (iron overload). Your healthcare provider should check the iron level in your blood before you start treatment with ACCRUFeR

Risk of overdose in children due to accidental swallowing. Accidental overdose of iron-containing products is a leading cause of death from poisoning in children under 6. Keep ACCRUFeR in a safe place and out of the reach of children

The most common side effects of ACCRUFeR include gas, diarrhea, constipation, discolored stools, stomach pain, nausea, vomiting, and stomach area discomfort or bloating. These are not all the possible side effects of ACCRUFeR. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch at www.fda.gov/medwatch or call 1-800-FDA-1088.

Benefits of ACCRUFeR

Why ACCRUFeR?

Here are a few reasons why ACCRUFeR may be right for you!

Uniquely formulated with a “maltol shield”

Unprecedented tolerability

Backed by clinical studies

Just enough iron

Iron you’ll actually take